Showing posts with label Albert Hoffman. Show all posts
Showing posts with label Albert Hoffman. Show all posts

Apr 29, 2008

LSD, R.I.P.

Albert Hoffman, the chemist who first discovered, and first tripped on, LSD has died at age 102.

A few passages from an obituary in the L.A. Times:

The twenty-fifth compound he synthesized, in 1938, was lysergic acid diethylamide (in German, lyserg-saure-diathylamid), or LSD-25. Because this compound had a chemical structure similar to an existing drug called Coramine, Hofmann had hoped that it would be a stimulant for the respiratory and circulatory systems.

-snip-

Prompted by what Hofmann later described as a "peculiar presentiment" that LSD-25 might have properties other than those established in the first investigations, he decided to look at it again.

On Friday afternoon, April 16, 1943, Hofmann had just completed synthesizing a new batch when, he subsequently wrote his supervisor, "I was forced to interrupt my work in the laboratory in the middle of the afternoon and proceed home, being affected by a remarkable restlessness, combined with slight dizziness.

"At home, I lay down and sank into a not-unpleasant intoxicated-like condition, characterized by an extremely stimulated imagination. In a dreamlike state I perceived an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors. After some two hours, this condition faded away."

Everything wasn't kaleidoscopes:

"Everything in the room spun around, and the familiar objects and pieces of furniture assumed grotesque, threatening forms," he wrote in his autobiography, "LSD -- My Problem Child." "They were in constant motion, animated, as if driven by an inner restlessness. The lady next door [became] a malevolent, insidious witch with a colored mask."